{"id":249,"date":"2020-09-10T16:36:57","date_gmt":"2020-09-10T14:36:57","guid":{"rendered":"https:\/\/mivegec.fr\/?page_id=249"},"modified":"2025-04-16T16:11:06","modified_gmt":"2025-04-16T14:11:06","slug":"perturbations-evolution-virulence-pev","status":"publish","type":"page","link":"https:\/\/mivegec.fr\/fr\/departements-scientifiques\/perturbations-evolution-virulence-pev","title":{"rendered":"Perturbations, Evolution, Virulence (PEV)"},"content":{"rendered":"

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[\/et_pb_fullwidth_post_title][et_pb_fullwidth_code admin_label=\u00a0\u00bbFil d’ariane\u00a0\u00bb module_id=\u00a0\u00bbbreadcrumb\u00a0\u00bb _builder_version=\u00a0\u00bb4.24.0″ vertical_offset_tablet=\u00a0\u00bb0″ horizontal_offset_tablet=\u00a0\u00bb0″ text_orientation=\u00a0\u00bbcenter\u00a0\u00bb box_shadow_horizontal_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_vertical_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_blur_tablet=\u00a0\u00bb40px\u00a0\u00bb box_shadow_spread_tablet=\u00a0\u00bb0px\u00a0\u00bb global_module=\u00a0\u00bb1485″ saved_tabs=\u00a0\u00bball\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]Accueil<\/a><\/span><\/span>[\/et_pb_fullwidth_code][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1″ module_id=\u00a0\u00bbnavDepartement\u00a0\u00bb _builder_version=\u00a0\u00bb4.16″ background_color=\u00a0\u00bb#225c74″ vertical_offset_tablet=\u00a0\u00bb0″ horizontal_offset_tablet=\u00a0\u00bb0″ custom_padding=\u00a0\u00bb0px|0px|0px|0px\u00a0\u00bb box_shadow_horizontal_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_vertical_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_blur_tablet=\u00a0\u00bb40px\u00a0\u00bb box_shadow_spread_tablet=\u00a0\u00bb0px\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_row _builder_version=\u00a0\u00bb4.16″ vertical_offset_tablet=\u00a0\u00bb0″ horizontal_offset_tablet=\u00a0\u00bb0″ custom_padding=\u00a0\u00bb40px|0px|40px|0px\u00a0\u00bb z_index_tablet=\u00a0\u00bb0″ box_shadow_horizontal_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_vertical_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_blur_tablet=\u00a0\u00bb40px\u00a0\u00bb box_shadow_spread_tablet=\u00a0\u00bb0px\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4″ _builder_version=\u00a0\u00bb4.16″ custom_padding=\u00a0\u00bb|||\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_text disabled_on=\u00a0\u00bboff|off|off\u00a0\u00bb admin_label=\u00a0\u00bbAnimateurs\u00a0\u00bb _builder_version=\u00a0\u00bb4.27.4″ vertical_offset_tablet=\u00a0\u00bb0″ horizontal_offset_tablet=\u00a0\u00bb0″ text_orientation=\u00a0\u00bbcenter\u00a0\u00bb background_layout=\u00a0\u00bbdark\u00a0\u00bb z_index_tablet=\u00a0\u00bb0″ text_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb text_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb text_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb link_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb link_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb link_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb ul_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ul_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ul_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb ol_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ol_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ol_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb quote_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb quote_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb quote_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_2_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_2_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_2_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_3_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_3_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_3_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_4_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_4_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_4_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_5_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_5_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_5_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_6_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_6_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_6_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb box_shadow_horizontal_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_vertical_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_blur_tablet=\u00a0\u00bb40px\u00a0\u00bb box_shadow_spread_tablet=\u00a0\u00bb0px\u00a0\u00bb global_module=\u00a0\u00bb1572″ saved_tabs=\u00a0\u00bball\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

Bin\u00f4me animateur du d\u00e9partement : <\/strong>Elodie CHAPUIS<\/a> & Vincent PEDERGNANA<\/a><\/p>\n

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Pr\u00e9sentation<\/a> Equipes<\/a> Projets<\/a> Collaborations scientifiques<\/a> Publications<\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1″ _builder_version=\u00a0\u00bb4.16″ global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_row column_structure=\u00a0\u00bb1_2,1_2″ _builder_version=\u00a0\u00bb4.16″ background_size=\u00a0\u00bbinitial\u00a0\u00bb background_position=\u00a0\u00bbtop_left\u00a0\u00bb background_repeat=\u00a0\u00bbrepeat\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb1_2″ _builder_version=\u00a0\u00bb4.16″ custom_padding=\u00a0\u00bb|||\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.16″ vertical_offset_tablet=\u00a0\u00bb0″ horizontal_offset_tablet=\u00a0\u00bb0″ z_index_tablet=\u00a0\u00bb0″ text_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb text_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb text_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb link_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb link_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb link_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb ul_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ul_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ul_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb ol_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ol_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ol_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb quote_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb quote_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb quote_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_2_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_2_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_2_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_3_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_3_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_3_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_4_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_4_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_4_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_5_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_5_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_5_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_6_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_6_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_6_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb box_shadow_horizontal_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_vertical_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_blur_tablet=\u00a0\u00bb40px\u00a0\u00bb box_shadow_spread_tablet=\u00a0\u00bb0px\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

Interactions h\u00f4te-parasite-environnement\u00a0: une vision int\u00e9grative pour comprendre les dynamiques et les effets des perturbations environnementales naturelles ou anthropiques.<\/h2>\n

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L’\u00e9cologie et l’\u00e9volution des interactions h\u00f4te-parasite conduisent \u00e0 une grande diversit\u00e9 d’histoires naturelles d’infections. Nous \u00e9tudions ces interactions h\u00f4te-parasite et l’impact des perturbations environnementales associ\u00e9es, avec une approche multiple:<\/p>\n

    \n
  1. mol\u00e9culaire\/cellulaire : par quels m\u00e9canismes les parasites manipulent le flux et la pr\u00e9cision du transfert d’informations biologiques intra-h\u00f4te, \u00e9largissant ainsi la diversit\u00e9 ph\u00e9notypique ? Quelles implications en termes de pathog\u00e9nicit\u00e9 ?<\/li>\n
  2. individu\/populations: l’\u00e9tude des communaut\u00e9s et des perturbations associ\u00e9es, qu’elles soient environnementales (cycles hydrologiques…) ou anthropiques (urbanisation, \u00e9changes commerciaux, pratiques agro-pastorales, politiques de sant\u00e9 publique), permet d’avoir une vision int\u00e9grative de la transmission et des risques d’infection.<\/li>\n<\/ol>\n

    Le suivi des r\u00e9ponses d’un syst\u00e8me aux perturbations permet souvent de mieux le comprendre. La pr\u00e9vision des cons\u00e9quences des changements environnementaux\/anthropiques est \u00e9galement une attente soci\u00e9tale majeure, tant en termes d’\u00e9cologie de la conservation (\u00e9pid\u00e9mies, esp\u00e8ces envahissantes), que de sant\u00e9 publique (vaccination, traitements,…) ou de sant\u00e9 v\u00e9t\u00e9rinaire (remplacement des races traditionnelles).<\/p>\n

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    Mots-cl\u00e9s<\/h2>\n

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    \u00c9volution, \u00e9cologie, sant\u00e9, virulence, r\u00e9sistance, tol\u00e9rance, perturbations, infections multiples, microbiote<\/strong><\/p>\n

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    Objectifs principaux<\/h2>\n

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    Nos travaux reposent sur la compl\u00e9mentarit\u00e9 des mod\u00e8les biologiques (plasmides, virus, bact\u00e9ries, macroparasites, vecteurs) mais \u00e9galement des m\u00e9thodes utilis\u00e9es. Nous combinons en effet des approches math\u00e9matiques de mod\u00e9lisation et analyse computationnelle en \u00e9pid\u00e9miologie, phylog\u00e9nomique et \u00e9volution de la virulence\u00a0; des approches empiriques, observationnelles et interventionnelles en \u00e9cologie et g\u00e9n\u00e9tique des populations et communaut\u00e9s; des approches exp\u00e9rimentales et m\u00e9canistiques en biologie mol\u00e9culaire et cellulaire\u00a0; ainsi que des analyses bio-informatiques de grands jeux de donn\u00e9es observationnelles ou exp\u00e9rimentales.<\/p>\n

    [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1″ module_id=\u00a0\u00bbimplantations\u00a0\u00bb _builder_version=\u00a0\u00bb4.16″ background_image=\u00a0\u00bbhttps:\/\/mivegec.fr\/wp-content\/uploads\/2020\/09\/carte.jpg\u00a0\u00bb vertical_offset_tablet=\u00a0\u00bb0″ horizontal_offset_tablet=\u00a0\u00bb0″ box_shadow_horizontal_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_vertical_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_blur_tablet=\u00a0\u00bb40px\u00a0\u00bb box_shadow_spread_tablet=\u00a0\u00bb0px\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_row column_structure=\u00a0\u00bb1_2,1_2″ _builder_version=\u00a0\u00bb4.16″ global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb1_2″ _builder_version=\u00a0\u00bb4.16″ custom_padding=\u00a0\u00bb|||\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.16″ vertical_offset_tablet=\u00a0\u00bb0″ horizontal_offset_tablet=\u00a0\u00bb0″ background_layout=\u00a0\u00bbdark\u00a0\u00bb z_index_tablet=\u00a0\u00bb0″ text_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb text_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb text_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb link_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb link_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb link_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb ul_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ul_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ul_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb ol_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ol_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb ol_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb quote_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb quote_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb quote_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_2_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_2_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_2_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_3_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_3_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_3_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_4_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_4_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_4_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_5_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_5_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_5_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb header_6_text_shadow_horizontal_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_6_text_shadow_vertical_length_tablet=\u00a0\u00bb0px\u00a0\u00bb header_6_text_shadow_blur_strength_tablet=\u00a0\u00bb1px\u00a0\u00bb box_shadow_horizontal_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_vertical_tablet=\u00a0\u00bb0px\u00a0\u00bb box_shadow_blur_tablet=\u00a0\u00bb40px\u00a0\u00bb box_shadow_spread_tablet=\u00a0\u00bb0px\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

    Implantations des \u00e9quipes PEV<\/h2>\n

     <\/p>\n